News

More ALS genes identified, expanding the foundation for treatment development

Researchers from Project MinE have identified new genetic abnormalities that play a role in the development of ALS. As a result, the proportion of patients for whom a genetic cause can be identified of the neuromuscular disease has increased from 20 to 25 percent. The discovery also improves understanding of the disease and may, in time, support the development of targeted treatments for a subset of patients.

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Project MinE satellite meeting at the 36th International Symposium on ALS/MND

On December 4th 2025, at the 36th International Symposium on ALS/MND in San Diego, Jan Veldink presented updates on Data Freeze 3 (DF3), recent advances in in-house WGS capacity, plans for Data Freeze 4 (DF4) and updates were presented from a number of working groups by Johnathan Cooper-Knock, Kevin Kenna, Alfredo Iacoangeli and Ross Byrne.

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