Project MinE* is a patient-driven groundbreaking genetic ALS research. The project is a worldwide collaboration between ALS centres and foundations.
All Project MinE data used in the listed publications were made accessible and available through funding by the Dutch ALS Foundation and co-funding by the PPP Allowance made available by Health~Holland, Top Sector Life Sciences & Health, to stimulate public-private partnerships.
Find us on research gate
Amyotrophic lateral sclerosis (ALS) is underpinned by an oligogenic rare variant architecture. Identified genetic variants of ALS include RNA-binding proteins […]Read more
To identify novel genes associated with ALS, we undertook two lines of investigation. We carried out a genome-wide association study […]Read more
no abstract avalaibleRead more
We have previously shown higher-than-expected rates of schizophrenia in relatives of patients with amyotrophic lateral sclerosis (ALS), suggesting an aetiological […]Read more
Identifying large expansions of short tandem repeats (STRs) such as those that cause amyotrophic lateral sclerosis (ALS) and fragile X […]Read more