Project MinE is a patient-driven groundbreaking genetic ALS research.
The project is a worldwide collaboration between ALS centres and foundations.
Find us on research gate.
Project MinE promotes broad, transparant and responsible data sharing.
Summary data of Project MinE manuscripts will be published shortly after each publication.
Manuscripts can be found under tab ‘publications’ of the Project MinE Variant Browser.
Project MinE Variant Browser based on 4,383 whole genomes from different European ancestry and GWAS summary statistics.
Project MinE participates in the Haplotype reference consortium , a large reference panel of human haplotypes.
ALS centres are very welcome to join Project MinE if they:
Please feel welcome to join our next Project MinE consortium meeting during the MND symposium in Boston december 2017.
For this study, genetic material from both people with ALS and control subjects will be used. Control subjects need to conform to specific requirements. A Standard Operating Procedure (SOP) has been defined for this and can be found here.
Along with genetic material, some minimal clinical data needs to be collected for each individual in Project MinE. This core clinical dataset has been defined for Project MinE and guidelines can be found here. This includes the Edinburgh Cognitive and Behavioural ALS Screen (ECAS).
In addition, each individual can be asked to fill in a questionnaire about life style and environmental factors (form for patients/controls, form for examiners), for international collaborative research into risk factors for ALS.
If you’d like to learn more about collaborative data collection, please contact the project office at firstname.lastname@example.org.