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100 percent of all donations to Project Mine will go directly towards the mapping and analysis of DNA profiles.

University of Turin and University of Milan Medical School at IRCCS

Project MinE Italy is run by our research partners at University of Turin and University of Milan Medical School at IRCCS Istituto Auxologico Italiano.

The ALS Centre in Milan, at the Department of Neurology-Stroke Unit of the University of Milan Medical School at the IRCCS Istituto Auxologico Italiano has large interests in many aspects of ALS, but specifically, in the past few years, in defining the genetics of both FALS and SALS. Prof. Silani contributed with his large team to the discovery of new genes in FALS (Profilin1, TUBA4A, TBK1, NEK1) and to the finalization of the two largest GWAS in SALS. Project MinE is considered an obligatory step in further defining the genetic basis of ALS, after completing the exome sequence of several hundred ALS patients. Envisioning a future where the therapy for ALS patients is based on a precision medicine approach, stratification of patients according to their genetic risk factors appears an obligatory step to design molecularly tailored interventions.

May we introduce our experts?

Our research partners at University of Turin and University of Milan Medical School at IRCCS Istituto Auxologico Italiano.

  • Adriano Chio

    Professor of Neurology, Medical and Scientific Director of the Department of Neuroscience, at the University of Torino and AOU San Giovanni Battista Torino, Italy

    Adriano Chio

    Professor of Neurology, Medical and Scientific Director of the Department of Neuroscience, at the University of Torino and AOU San Giovanni Battista Torino, Italy
  • Vincenzo Silani

    Professor and Chairman of Department of Neurology, Stroke Unit and Laboratory of Neuroscience, University of Milan Medical School at IRCCS Istituto Auxologico Italiano

    Vincenzo Silani

    Professor and Chairman of Department of Neurology, Stroke Unit and Laboratory of Neuroscience, University of Milan Medical School at IRCCS Istituto Auxologico Italiano

    Vincenzo Silani is Full Professor of Neurology and the Chairman of the Department of Neurology-Stroke Unit and Laboratory of Neuroscience of the University of Milan Medical School at the IRCCS Istituto Auxologico Italiano, Director of “Dino Ferrari” Centre for Neuromuscular and Neurodegenerative Disease of the University of Milan Medical School and Director of the ALS Centre.

    Prof. Silani graduated M.D. in 1977 at the University of Milan Medical School and he obtained the Specialties of Neurology (1981) and Neurosurgery (1989). Post-doctoral Fellow in the Department of Neurology-Baylor College of Medicine in Houston (1979-81), Visiting Professor in Neurology at the Baylor College of Medicine (1999), he was CoChairman (2002-2005) and Chairman (2005-2007) of the European ALS Consortium (EALSC). Director European Neurological Society (ENS) – Subcommittee for Motor Neuron Disease (2008-2013), he is now Co-Director of the European Academy of Neurology (EAN) Subspeciality Panel ALS and Frontotemporal Dementia (2013-present).  Author of more than 240 scientific publications, he was invited lecturer in more than 200 international meetings.

A big thank you to everyone who has contributed to Project MinE

  • ciro armigero
    € 975
     • Italy
  • Andrea Gabrie Busne
    € 1
     • Italy
  • Andrea Gabriele Busnelli
    € 1
     • Italy
  • grant contribution AriSLA
    € 100,000
     • Italy