Dr. Dupré has made major contributions both locally and internationally to the fields of neuromuscular and neurogenetic medicine, and has published more than 100 peer-reviewed papers and five book chapters.

He is currently the director of the Neuromuscular & Neurogenetic Disease Clinic of the CHU de Québec – U Laval, taking care of thousands of patients from the Eastern Quebec area afflicted with rare and common diseases of the nervous system.

Dr. Dupré was involved in the 2008 discovery that the gene TDP-43 is involved in ALS. He also helped to establish the ALS clinic at the CHU de Québec, providing care to patients in Eastern Quebec.