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Trinity College Dublin, RMN & iMNDA

The Academic Unit of Neurology of Trinity College Dublin, Research Motor Neurone (RMN) and the Irish Motor Neurone Disease Association (IMNDA) are partners in Project MinE and aim to analyse 400 DNA samples of ALS patients and 200 DNA samples of control subjects.

The Academic Unit of Neurology is part of the School of Medicine at Trinity College Dublin and houses the Irish ALS Research Group. The Unit has close links with colleagues at the Institute of Neuroscience, and the Neurology Units at St. James and Tallaght Hospital and the National Neuroscience Centre at Beaumont Hospital. The Irish ALS Research Group includes international experts in cognition, imaging, clinical management, epidemiology and genetics of ALS. Our group has conducted the first population based longitudinal study of cognition and behaviour in ALS, was the first to show that the phenotype and natural history of incident and prevalent patients with ALS/MND differs; that attendance at a multidisciplinary clinic independently improves survival, and that the presence of executive impairment is an important determinant of disease progression.

Project MinE is important to our group as we have already shown that the gene ANG as an important genetic modifier in ALS, that genetic admixture is likely to be protective in ALS, and that some neuropsychiatric conditions occur with higher frequency in ALS kindred, suggesting a commonality in genetic susceptibility. As the Irish population is genetically homogeneous and the Irish Register collects detailed clinical information about the condition, our ongoing work in the genetics of ALS in the Irish population is likely to provide further important insights into ALS that can in turn translate into earlier diagnoses and new treatments.

Research Motor Neurone is an Irish charity founded in 2007, with the purpose of promoting and facilitating research into the causes and treatments of motor neurone disease (MND). RMM provides seed funding for ongoing research to find the cause, treatment options and methods of improving the quality of life of MND sufferers and their families.

The Irish Motor Neurone Disease Association is the primary support organisation in Ireland providing care for people with Motor Neurone Disease, their families, friends and carers. Key services include home visiting by an MND dedicated nurse, financial assistance towards home care help and the provision of specialist medical equipment and appliances on loan free of charge to clients. The Association also supports research into the causes and treatment of the disease through specific financial bursaries.

May we introduce our experts?

Project MinE research in Ireland is performed at the Academic Unit of Neurology of Trinity College Dublin.

For questions about Project MinE in Ireland, please contact

ireland@projectmine.com

Telephone: 086 8212659
www.facebook.com/ProjectMineIreland
Twitter: @ProjectMineIRE

  • Orla Hardiman

    Professor / Hoofd Academische Neurologie, Trinity College Dublin, Consultant Neuroloog, Beaumont Hospital Dublin

    Orla Hardiman

    Professor / Hoofd Academische Neurologie, Trinity College Dublin, Consultant Neuroloog, Beaumont Hospital Dublin

      Professor Orla Hardiman is leider van de Ierse ALS onderzoeksgroep en is hoofd van de nationale multidisciplinaire ALS kliniek in Ierland. Prof. Hardiman is de grondlegger van het Ierse ALS register, het langstlopende ALS register wereldwijd. Onderzoek in haar groep richt zich onder andere op ‘deep phenotyping’, epidemiologie en pathogenese van ALS, en dan specifiek op het identificeren van genetische en omgevingsrisicofactoren. Recent werk betreft de klinische en genetische overlap tussen ALS en frontotemporale dementie. DE onderzoeksgroep werkt actief samen met verschillende grote ALS centra in Europa en de VS.

    • Alice Vajda

      Post Doc, Onderzoekscoördinator, Trinity College Dublin

      Alice Vajda

      Post Doc, Onderzoekscoördinator, Trinity College Dublin

      Onze partners

      In Ierland wordt de fondsenwerving voor Project MinE geleid door Research Motor Neuron en de Irish Motor Neurone Disease Association.

      Onze grote dank gaat uit naar iedereen die Project MinE reeds ondersteund heeft

      • Maura McHugh and Friends, Donegal
        € 8 850
         • Ierland
      • Anonymous
        € 100
         • Ierland
      • The Good Run 2017
        € 10 815
         • Ierland
      • in memory of Tony O'Connor
        € 25 000
         • Ierland
      • Anonymous
        € 1 000
         • Ierland
      • Anonymous
        € 500
         • Ierland
      • Sonya Gallagher
        € 50
         • Ierland
      • Anonymous
        € 1 950
         • Ierland
      • Anne & Jason Conway
        € 50
         • Ierland
      • Suzanne Garrett
        € 100
         • Ierland
      • Maureen Murtagh
        € 75
         • Ierland
      • Ailish Garrett
        € 300
         • Ierland
      • David Carey
        € 100
         • Ierland
      • Emma Burke
        € 50
         • Ierland
      • Noel & Geraldine Garrett
        € 200
         • Ierland
      • The Browns
        € 50
         • Ierland
      • Christy & Mary Garrett
        € 50
         • Ierland
      • Mickey & Bernie Garrett
        € 100
         • Ierland
      • Simone Mordaunt
        € 30
         • Ierland
      • Anonymous
        € 55
         • Ierland
      • Mairead MC donagh
        € 100
         • Ierland
      • Helen Sullivan
        € 20
         • Ierland
      • Marie Garrett
        € 50
         • Ierland
      • Trish Garrett
        € 50
         • Ierland
      • Lilly Garrett
        € 10
         • Ierland
      • Eugene Rochford
        € 100
         • Ierland
      • RayandHelen Norton
        € 50
         • Ierland
      • Elaine Garrett
        € 75
         • Ierland
      • John Garrett
        € 10
         • Ierland
      • Karen Edelblum
        € 50
         • Ierland